User experiences of Fiasp

The below table shows the details from various users of Fiasp that have shared their experiences of the new insulin to make it easier for those who are about to start using it to understand it in the real world.

Experiences with Fiasp
Entries
6
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# How is your insulin delivered? How long have you been using Faster Insulin Aspart? Are you using CGM while using Fiasp? Please select what your FIasp experience relates to? (You can select multiple responses) Please provide your experience with Fiasp. Provide as much detail as you can so that those coming along later can understand what happened, what you changed and what to watch out for. If you were to start using Fiasp again, what do you wish you'd known before starting?
1
Hybrid Closed Loop
1.5 weeks
Yes
Action time
Insulin Tail
Hypoglycaemia
Unexpected results after bolusing
Changes required on pump (e.g. basal rates, ISF, DIA, I:C Ratio)

Fiasp takes effect for me within 20mins of bolusing.

It seems to have a shorter effective tail.

My hypo symptoms seem to be starting earlier, but this may be temporary.

I've noticed that insulin stacking can create extra sensitivity.

I adjusted my DIA to two hours due to the changes in action, but other settings are the same.

The main thing to watch out for is the speed of action. I've noticed that it is very consistent in taking effect after 20 mins, so given the time it takes for food absorption to start, I rarely bolus more than ten minutes prior to eating .

I wish that I'd known that the effective tail is quite short.

2
Hybrid Closed Loop
1 week
Yes
Action time

Great experience. Starts fast. Do not prebolus under any condition.

Pretty straightforward.

3
Hybrid Closed Loop
8 days
Yes
Action time
Insulin Tail
Hypoglycaemia
Unexpected results after bolusing
Changes required on pump (e.g. basal rates, ISF, DIA, I:C Ratio)

I've noticed the quicker action (which is expected). I did have one meal where food did not absorb quickly enough and was seriously considering giving glucagon since my blood sugars dropped below 1.1mmol/L. Because I have gastroparesis, I now wait until my blood sugars start to rise a bit after eating and then bolus, and because Fiasp is so quick, I still don't peak at a crazy high blood sugar (which is kind of nice).
I've had to drop back my DIA with the Fiasp compared to Novorapid. Novorapid I had at 4.5hrs and I tried Fiasp at 4, but have just dropped it again to 3.5hrs.

I wish I'd known how aggressively it works up front.

4
Pump
4 days 
Yes
Action time
Other things worth considering

Works faster, works more effectively at high bg levels (less insulin resistance at higher bg levels).

Less insulin resistance at higher levels.

5
Hybrid Closed Loop
8 days
Yes
Action time
Changes required on pump (e.g. basal rates, ISF, DIA, I:C Ratio)
Other things worth considering

We use Fiasp with Loop with our 11 year old son. We adjusted our bolus time to 0-8 minutes before a meal (novorapid was 10-20 minutes pre-meal), depending on current BG, trend, and meal. We have also done minor adjustments to ISF. We have found a significant reduction in post meal spikes and also a nice response to Loop's high temp basals (due to the faster action time of Fiasp). We continue to monitor and make adjustments as necessary. We did not have issues with lows because we anticipated the faster action time and adjusted for it. It's certainly a new, very useful tool to have in the diabetes tool box and like any diabetes tool requires careful monitoring and caution while learning how it works for you.

I had researched and done plenty of reading on Fiasp so felt prepared, and had no surprises, so nothing really.

6
Pump
A week
Yes
Action time
Hypoglycaemia
Unexpected results after bolusing
Changes required on pump (e.g. basal rates, ISF, DIA, I:C Ratio)

Have shortened action time to 2 hours but need to do proper ISF test. Think might need to change I/C ratio from roughly 1/4 units to 1/5 or 6. Am using extended bolus's much more. Have had a couple of unrecognised bad lows, symptoms slightly different. My targets = 3.9 to 7.5 of which I usually achieve around 50%, this week's has been 63% which is better, less highs but more lows. Work to be done!

Reduce bolus units by 10% to start, increase basal for dawn phenomenon. Check ISF, I/ C ratios fairly soon after starting. Carry fast acting fudge, juice for those hypos.



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